: To evaluate the ability of a newly designed device, O-Glass to detect relative afferent pupillary defect (RAPD)

In this prospective observational study, 44 patients (diagnosed RAPD- positive) were enrolled. Three groups of masked examiners observed patients for an RAPD by swinging flashlight method (SFM) and O-Glass device. The instrument captured and recorded eye pictures. The images were processed and analyzed using computerized software to calculate pupillary measurements. The results were compared between two methods and three different groups of examiners.

Twenty six patients were known cases of Multiple Sclerosis (MS)-related optic neuritis, fourteen of them had glaucoma and four patients had history of traumatic optic neuropathy. The mean age (SD) of the study participants (18 female and 26 male) was 35 (10). All three groups of examiners were satisfied with successful diagnosis by O-Glass.

O-Glass is a simple eye-glass along with mobile friendly software that any care giver can use to perform the tests to identify an RAPD automatically and rapidly. The ability to store and archive the objective and quantifiable results for referencing and follow-ups, makes the device more valuable.